Rheumatoid arthritis and osteoporosis
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Rheumatoid arthritis and osteoporosis.
Rheumatoid arthritis is an inflammatory arthritis which changes the biomechanical properties of bones and leads to the alterations in bone components through the increased production of pro-inflammatory cytokines or by hormone mediated mechanisms (1-3). In addition to traditional risk factors of osteoporosis, physical disability, inadequate treatment, and disease activity are also responsible f...
full textOsteoporosis in rheumatoid arthritis.
OBJECTIVE To answer and comment on a number of controversial issues in relation to osteoporosis and rheumatoid arthritis (RA), including: Is osteoporosis an extra-articular manifestation of rheumatoid arthritis? Does periarticular osteoporosis reflect disease activity in early arthritis? Is there a threshold for corticosteroid-induced osteoporosis? Can anti-resorbing drugs prevent rheumatoid ar...
full textOsteoporosis in rheumatoid arthritis and ankylosing spondylitis.
Bone is a target in many inflammatory rheumatic diseases, such as rheumatoid arthritis (RA) and ankylosing spondylitis (AS). The generalized effect of inflammation on bone may result in a decreased quality of bone and is associated with an increased risk of fractures and deformities, both in RA and AS. RA is characterized by periarticular osteopenia, systemic osteoporosis and bone erosions. Per...
full textRisk of infection in postmenopausal women with rheumatoid arthritis and osteoporosis taking denosumab and bDMARDS
Background: There is no clear consensus regarding the potential of denosumab for increasing the risk of infection in patients who concurrently receive biologic disease-modifying anti-rheumatic drugs (bDMARDs). In this study, we compared the rate of infection in postmenopausal women with rheumatoid arthritis who received concurrent bDMARDs and denosumab with those who received bDMARDs alone. ...
full textPrevalence and associated factors of osteoporosis in female patients with rheumatoid arthritis
Background: Osteoporosis (OP) is a common complication of inflammatory arthritis such as rheumatoid arthritis (RA). In this study we evaluated Osteoporosis and its related factors in RA patients. Methods: This cross - sectional study was carried out from 2010 to 2011 on 121 women with RA aged 45-75 years. These patients were selected and divided in two groups according to their bone mineral de...
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Journal title
volume 3 issue None
pages 445- 446
publication date 2012-01
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